Triangle Research Labs, LLC and Biopredic International have completed an agreement for TRL to distribute the NoSpin HepaRG™ cells in North America. The NoSpin HepaRG™ represent an important improvement over the original cryopreserved HepaRG™ cells.
NoSpin HepaRG™ is a fully-functional, adult-phenotype, human hepatic cell line. The NoSpin HepaRG™ exhibits many characteristics similar to primary human hepatocytes and can be used for many of the same applications. The NoSpin HepaRG™ is provided in a convenient, terminally differentiated, cryopreserved format that does not require the user to centrifuge, resuspend, or count the cells after thawing. Each lot has consistent yield, viability, and functionality across multiple applications.
The cells have been the subject of dozens of recent scientific papers and posters, demonstrating their suitability for all in-vitro analyses for which the more variable and expensive cryopreserved primary human hepatocytes have been used.
The No-Spin HepaRG™ utilize a proprietary cryopreservation process that leverages the consistency and predictability of HepaRG responses and their post-thaw viability (typically 93-98%) with novel techniques developed by Biopredic scientists. All other forms of cryopreserved hepatocytes require thawing, suspension, centrifugation, resuspension, and counting (to account for variability introduced) steps; the No-Spin HepaRG™ simply need to be thawed and then they are ready for use. Not only will this benefit high-volume labs which now undertake many laborious and expensive steps to use hepatocytes, but all labs will gain from this format which reduces the risk of errors or variability.
For more information on HepaRG™, please follow the link below:
NoSpin HepaRG™ Products Catalog
|NSHPRG||NoSpin HepaRG™ Cells, Cryopreserved – Minimum 8 million viable cells|
|MH100||NoSpin HepaRG™ Media, Base Medium (100mL) with Supplement|
|MHTAP||NoSpin HepaRG™ Media, Thawing and Plating Additive|
|MHMET||NoSpin HepaRG™ Media, Plated Metabolism Additive|
|MHPIT||NoSpin HepaRG™ Media, Pre-Induction and Tox Additive|
|MHIND||NoSpin HepaRG™ Media, Induction Additive (Serum Free)|
Visit the Lonza e-store to place your order online or contact Customer Service at (800)638-8174.
For instructions on how to handle the NoSpin HepaRG™ cells, including thawing and plating: